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課程名稱 |
高等化學生物學專論二
DISCUSSION IN ADVANCED CHEMICAL BIOLOGY(II) |
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開課學期 |
97-2 |
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授課對象 |
理學院 化學所化學生物學組 |
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授課教師 |
羅禮強 |
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課號 |
Chem8036 |
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課程識別碼 |
223 D1620 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
必修 |
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上課時間 |
星期一3(10:20~11:10)星期五3,4(10:20~12:10) |
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上課地點 |
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備註 |
本課程中文授課,使用英文教科書。有機組不得修習此門。上課教室：普505教室。
限博士班
總人數上限：30人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/972advbiochem2 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
(1) Synthetic Design
Retrosynthetic analysis
Steps in planning a synthesis
Stereochemical considerations
(2) The Concept of Protecting Functional Groups
Protection of NH groups
Protection of OH groups of alcohols
Protection of carbonyl groups
Protection of carboxyl groups
Protection of double bonds
(3) Functional Group Transformations
Oxidation and reduction
The chemistry of (83e0)-bonds and related reactions
(4) Formation of Carbon-Carbon Single Bonds
Enolates
Organometallic reagents
(5) Formation of Carbon-Carbon (83e0)-Bonds
Formation of double bonds
Formation of triple bonds
(6) Synthesis of Biomolecules
Combinatorial chemistry
Peptide chemistry
Carbohydrate synthesis
Nucleoside and nucleotide chemistry |
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課程目標 |
(1) Synthetic Design
Retrosynthetic analysis
Steps in planning a synthesis
Stereochemical considerations
(2) The Concept of Protecting Functional Groups
Protection of NH groups
Protection of OH groups of alcohols
Protection of carbonyl groups
Protection of carboxyl groups
Protection of double bonds
(3) Functional Group Transformations
Oxidation and reduction
The chemistry of (83e0)-bonds and related reactions
(4) Formation of Carbon-Carbon Single Bonds
Enolates
Organometallic reagents
(5) Formation of Carbon-Carbon (83e0)-Bonds
Formation of double bonds
Formation of triple bonds
(6) Synthesis of Biomolecules
Combinatorial chemistry
Peptide chemistry
Carbohydrate synthesis
Nucleoside and nucleotide chemistry |
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課程要求 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
期中考 |
30% |
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2. |
期末考 |
30% |
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3. |
隨堂測驗+作業 |
50% |
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